Kollidon sr. 4 Spray dried polyvinyl acetate containing povidone (Kollidon®SR) Polyviny...
Kollidon sr. 4 Spray dried polyvinyl acetate containing povidone (Kollidon®SR) Polyvinyl acetate having a average molecular weight of about 50000 is produced by radical polymerization as aqueous dispersion in water (Kollicoat® SR 30D), addition of about 19% of povidone (Kollidon®30) and spray drying. For the exact composition please refer to the product specification. 02. Suitable for continious manufacturing. It is particularly suitable for manufacturing of pH-independent sustained-release matrix tablets by direct compression or hot melt extrusion. Kollidon® SR is insoluble in water and very soluble in N-methylpyrrolidone. The examples of soluble grade of kollidon (Povidone) are kollidon 12 PF, 17 PF, 25, 30, 90F, kollidon VA64 (Copovidone), insoluble grade (Crospovidone) are kollidon CL, CL-F, CL-SF, CL-M and kollidon SR grade which is mixture of polyvinyl acetate and povidone in ratio of 8:2 for sustain release purpose. Polyvinyl acetate is a very plastic material that produces a coherent matrix even under low compression forces. 3. 1.
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